Question: Anyone with successful treatment with St. John's Wort (herbal supplement) + any opinions on low-dose Zoloft?

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Answer #1:

nope

Answer #2:

when i took zoloft i lost a whole bunch a weight on it bc it made me never hungry

Answer #3:

First of all, Zoloft doesn't "flood" your brain with serotonin, it does not affect how much serotonin is made or released. Zoloft works by inhibiting the reuptake of serotonin from the transmitting neuron (hence the drug class SSRI- Selective Serotonin Reuptake Inhibitors). Zoloft does not induce sexual dysfunction or apathy in all patients, regardless of dosage. If you are experiencing these side effects, switching to a different SSRI (Paxil, Celexa, etc) or even an SNRI (Cymbalta etc) could be a strategy. If you really want to try a very low dose of the Zoloft you could opt for the liquid, so you would not have to worry about cutting a tablet.

Additionally, if you have been diagnosed with MDD and OCD, St Johns Wort is probably not a good choice for you. It has only been shown effective in mild to moderate depression, and the results are still conflicting. It also has many drug-drug interactions, so make sure to discuss it with your physician if you decide to try it.





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